Assessment of MTR Rs1805087 SNP as Possible Modifier of Sickle Cell Disease Severity in a Nigerian Population.

V O Osunkalu,A A Ogbenna,N O Davies,F O Olowoselu, O E Aiyelokun,O J Akinsola,I A Taiwo

West African journal of medicine（2022）

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Abstract

While HHcy is significantly associated with phenotypic expression of HbSS, the MTR 2756 SNPs did not appear to independently influence homocysteine level or disease severity in HbSS subjects.

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Key words

Homocysteine,Methionine synthase gene,Sickle cell disease,Sickle cell disease severity

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