Differential isoform expression of Allergin-1 during acute and chronic inflammation.

Ruben J Geerdink,Maria Inês Pascoal Ramos,Luuk L van den Hoogen,Timothy R D J Radstake,Shiro Shibayama,Akira Shibuya,Louis Bont,Linde Meyaard

Immunity, inflammation and disease（2022）

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摘要

Allergin-1 isoform expression is unaffected by chronic inflammatory conditions. In stark contrast to fellow inhibitory receptor LAIR-1, Allergin-1 does not regulate neutrophilic inflammation in a mouse model of RSV bronchiolitis.

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关键词

inhibitory receptor,neutrophils,nonclassical monocytes,respiratory syncytial virus,systemic lupus erythematosus

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