Cellular and Molecular Mechanisms of MEK1 Inhibitor–Induced Cardiotoxicity

JACC: CardioOncology（2022）

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摘要

These data describe pathologic changes observed in trametinib cardiotoxicity, supporting the exploration of drug holidays and alternative pharmacologic strategies for disease prevention.

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关键词

cardiomyopathy,cardiotoxicity,MEK1,trametinib

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