[Experimental Study of Using Aloe Vera Gel to Treat Diabetic Chronic Cutaneous Ulcers in Bama Miniature Pigs].
Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition(2022)
摘要
AVG topical application can shorten the time needed for complete healing of diabetic chronic wounds in Bama minipigs. The wound healing speed of the alternate-day treatment group was faster than that of the daily treatment group. No adverse reactions were observed over the course of the treatment. The mechanism may be related to the up-regulation of the expressions of miR21, miR126, and miR210 and the down-regulation of miR29a and miR155 in wound granulation tissue.
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关键词
Aloe vera gel,Bama minipigs,Chronic cutaneous ulcer,Diabetes mellitus,Wound healing,microRNAs
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