A HANC Risk Stratification Score for Antiplatelet Therapy Optimization with Low-Dose Prasugrel in Taiwanese Acute Coronary Syndrome Patients from the Switch Study.

Wen-Lieng Lee,Yi-Chih Wang,Chieh-Shou Su,Hsin-Fu Lee,Ying-Chang Tung,Ping-Yen Liu,Cheng-Huang Su,Feng-Yu Kuo,Wei-Shiang Lin,Pao-Hsien Chu,Tse-Min Lu,Ping-Han Lo,Shuji Tsukiyama,Wei-Chen Yang,Li-Chung Cheng,Wei-Hsian Yin,Yen-Hung Lin

Acta Cardiologica Sinica（2022）

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摘要

The HANC score may serve to alert clinicians to patients at potentially higher HPR risk on clopidogrel, but not prasugrel. Further research to validate this score and assess its correlation with clinical outcomes is warranted.

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关键词

Acute coronary syndrome,CYP2C19,Clopidogrel,Dual anti-platelet therapy,East Asian paradox,High on-treatment platelet reactivity,Prasugrel,Risk stratification

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