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Causal associations between blood pressure and the risk of myocardial infarction: A bidirectional Mendelian randomization study.

Zhi-Qiang Yang,Ting-Ting Fan,Zheng Wang, Wan-Ting Zhou, Zhen-Xian Wang,Yan Tan,Qi Wu,Bang-Long Xu

Frontiers in cardiovascular medicine（2022）

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Abstract
Elevated SBP or DBP levels increase the risk of MI, but there is no causal relationship between MI and changes in BP including PP. Independent of other risk factors, optimal BP control might represent an important therapeutic target for MI prevention in the general population.
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Key words
bidirectional Mendelian randomization,blood pressure,causation,genome-wide association study,myocardial infarction
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