Identification of a naturally-occurring canine model for early detection and intervention research in high grade urothelial carcinoma.

Deepika Dhawan,José A Ramos-Vara,Sagar M Utturkar,Audrey Ruple,Sarah A Tersey,Jennifer B Nelson,Bruce R Cooper,Hock Gan Heng,Elaine A Ostrander,Heidi G Parker,Noah M Hahn,Larry G Adams,Christopher M Fulkerson,Michael O Childress,Patty L Bonney, Christine Royce,Lindsey M Fourez,Alexander W Enstrom,Lisbeth A Ambrosius,Deborah W Knapp

Frontiers in oncology（2022）

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摘要

The study defined a novel naturally-occurring animal model to complement experimental models for early detection and intervention research in InvUC. Research incorporating the canine model is expected to lead to improved outcomes for humans, as well as pet dogs, facing bladder cancer.

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关键词

animal models,bladder cancer,cancer prevention,cancer screening,dog,early intervention,transitional cell carcinoma,urothelial carcinoma

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