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Western blot using Trypanosoma cruzi chimeric recombinant proteins for the serodiagnosis of chronic Chagas disease: A proof-of-concept study.

Ramona Tavares Daltro,Emily Ferreira Santos,Ângelo Antônio Oliveira Silva,Natália Erdens Maron Freitas,Leonardo Maia Leony, Larissa Carvalho Medrado Vasconcelos,Alejandro Ostermayer Luquetti,Paola Alejandra Fiorani Celedon,Nilson Ivo Tonin Zanchin, Carlos Gustavo Regis-Silva,Fred Luciano Neves Santos

PLoS neglected tropical diseases（2022）

Cited 1|Views18
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Abstract
The present phase I (proof-of-concept) study demonstrated the high diagnostic potential of these four IBMP antigens to discriminate between T. cruzi-positive and -negative samples, making them candidates for phase II and confirmatory testing with WB.
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Key words
trypanosoma cruzi chimeric,chronic chagas disease,chagas disease,serodiagnosis,recombinant proteins,proof-of-concept
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