Fludarabine and antithymocyte globulin-based conditioning regimen combined with post-transplantation cyclophosphamide for haploidentical allogeneic hematopoietic stem cell transplantation in patients with high-risk acute myeloid leukemia and myelodysplastic syndrome

Current Research in Translational Medicine(2023)

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摘要
High-dose stem cells can promote blood cell implantation. The modified ATG-PTCy combination was associated with decreased risk of aGVHD and cGVHD, no increased risk of recurrence, and improved GRFS. It represents an effective strategy for high risk AML and MDS.
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关键词
Acute myeloid leukemia,Conditioning regimens,Fludarabine,haploidentical allogeneic hematopoietic stem cell transplantation,Post-transplantation cyclophosphamide
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