Human Fecal Mucin Glycosylation as a New Biomarker in Inflammatory Bowel Diseases

Catherine Robbe Masselot,Camille Cordier,Benjamin Marsac,Maria Nachury,Renaud Leonard,Boualem Sendid

INFLAMMATORY BOWEL DISEASES（2022）

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摘要

Lay Summary For the first time, fecal mucins of Crohn's disease patients were analyzed by mass spectrometry. Compared with control subjects, Crohn's disease patients showed a significant decrease in sialylated glycans that we propose as new noninvasive tool for screening of intestinal diseases.

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Crohn's disease,inflammatory bowel syndrome,mucin glycans,human stools,diagnosis

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