Resveratrol alleviated 5-FU-induced cardiotoxicity by attenuating GPX4 dependent ferroptosis.

Dongning Li,Chengzhu Song,Jie Zhang,Xiaoyan Zhao

The Journal of nutritional biochemistry（2022）

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摘要

Res possessed the cardioprotective potential against 5-FU induced cardiotoxicity. Moreover, Res attenuates 5-FU-induced cardiotoxicity via inhibiting GPX4 dependent ferroptosis.

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关键词

Cardiotoxicity,Ferroptosis,GPX4,Oxidative stress,Resveratrol

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