Preliminary analysis of hippocampus synaptic apoptosis and microglial phagocytosis induced by severe restraint stress.

Shingo Enomoto,Masahiro Ohgidani,Noriaki Sagata,Shogo Inamine,Takahiro A Kato

Neuropsychopharmacology reports（2023）

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摘要

Severe restraint stress enhanced pre-synaptic apoptosis in mouse CA3 stratum lucidum region, but did not promote microglial phagocytosis. The phenomenon microglia fail to phagocytose weakened and unnecessary synapses may be related to pathology of stress.

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关键词

apoptosis,microglia,phagocytosis,stress,synapse

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