Serine hydroxymethyltransferase 1 promotes low-grade glioma progression by activating mTORC1 signaling.
Neurological research(2022)
Abstract
SHMT1 promoted proliferation, invasion and migration of LGG cells via activating mTORC1 signaling pathway. This provided a novel perspective for the treatment of LGG.
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Key words
Low-grade glioma,mammalian target of rapamycin complex 1,proliferation,serine hydroxymethyltransferase 1
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