The Multidrug Efflux Regulator AcrR of Escherichia coli Responds to Exogenous and Endogenous Ligands To Regulate Efflux and Detoxification

Dana E. Harmon,Cristian Ruiz, Patricia A. Bradford

mSphere（2022）

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摘要

Multidrug efflux pumps can remove antibiotics and other toxic molecules from cells and are major contributors to antibiotic resistance and bacterial physiology. Therefore, it is essential to better understand their function and regulation.

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关键词

AcrR,ligand,polyamines,ethidium bromide,multidrug efflux pump,AcrAB-TolC,Escherichia coli

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