Relationship between sexual differences and cardiovascular risk factors in the prevalence of asymptomatic coronary disease

•A total of 6434 asymptomatic subjects without known CAD underwent CCTA.•The prevalence of CAD (stenosis ≥50%) were compared by sex according to the number of conventional cardiovascular risk factors.•There were 1740 women (27.0%) and 4694 men (73.0%) in the study.•Asymptomatic CAD was identified in 65 women (3.7%) and 429 men (9.1%), and the association was significant (P < 0.001).•As the number of risk factors increased, the risk difference gap in women and men decreased. (P interaction <0.001).