Differential Expression of Serum Proteins in Chronic Obstructive Pulmonary Disease Assessed Using Label-Free Proteomics and Bioinformatics Analyses.

Renming Li,Xiaomin Zhao,Pengcheng Liu, Dandan Wang,Chen Chen,Yu Wang,Ningning Zhang,Bing Shen,Dahai Zhao

International journal of chronic obstructive pulmonary disease（2022）

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摘要

Our findings suggested pathogenic mechanisms underlying COPD stages and indicated three key proteins that may warrant further study as potential biomarkers for early diagnosis or prognosis of COPD or as therapeutic targets.

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关键词

LC-MC/MS,bioinformatics,chronic obstructive pulmonary disease,differentially expressed proteins,proteomics,respiration

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