Longitudinal Changes in Immune Activation Serum Biomarkers Prior to Diagnosis and Risk of B-cell NHL Subtypes.

Lynn I Levin,Christina M Ramirez, Eileen L Liao, Hongyu Guo, Bong K Kim, Aizen J Marrogi,Larry I Magpantay,Elizabeth C Breen,Otoniel Martínez-Maza

Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology(2023)

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摘要
The increasing trajectories of the B-cell activation molecules, sCD30, CXCL13, and to a lesser extent IL10, may indicate early disease-induced effects or reflect the chronic stimulation of B-cells that promotes the development of FL and DLBCL subtypes.
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关键词
immune activation serum biomarkers,b-cell
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