Secondhand smoke exposure is independently associated with stroke among non-smoking adults in West Africa.

Akinkunmi Paul Okekunle,Osahon Jeffery Asowata,Adekunle G Fakunle,Onoja Matthew Akpa,Fred S Sarfo,Albert Akpalu,Kolawole Wahab,Reginald Obiako,Morenikeji Komolafe,Lukman Owolabi,Godwin O Osaigbovo,Hemant K Tiwari,Joshua Akinyemi,Carolyn Jenkins,Oyedunni Arulogun,Philip Ibinaiye,Lambert Appiah,Atinuke M Agunloye,Abiodun M Adeoye,Joseph Yaria,Benedict Calys-Tagoe,Ezinne O Uvere,Godwin Ogbole,Francis Agyekum,Taofeek A Sanni,Ganiyu A Amusa,Mayowa Ogunronbi,Samuel Olowookere,Olayemi Balogun,James A Ogunmodede, Oladotun V Olalusi,Diala Samuel, Aliyu Mande,Musbahu Rabiu,Philip Adebayo,Adeniyi Sunday,Lucius Chidiebere Imoh,Ayodipupo S Oguntade, Abiodun Ajose,Arti Singh,Oluwayemisi T Adeegbe,Yaw Mensah,Michael B Fawale,Salaam Abdul,Joyce Ikubor,Afolaranmi Tolulope,Isah S Yahaya,Cynthia Akisanya, Chidi J Odo,Richard Efidi,Innocent I Chukwuonye,Vincent Shidali,Akintunde Adebowale,Kenneth A Ohagwu, Osimhiarherhuo O Adeleye,Henry Iheonye,Adeseye Akintunde,Eunice Olabinri,Josephine Akpalu,Julius Adesina,Ugochukwu Onyeonoro,Akinola Onasanya,Donna K Arnett,Daniel Lackland,Rufus Akinyemi,Bruce Ovbiagele,Mayowa Owolabi

Journal of the neurological sciences（2022）

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摘要

BACKGROUND:Stroke is a leading cause of disability and mortality worldwide, but little is known about the contribution of secondhand smoke exposure (SHSE) to stroke epidemiology among indigenous Africans. OBJECTIVE:To evaluate the association of SHSE with stroke among indigenous Africans. METHODS:We analyzed the relationship of SHSE with stroke among 2990 case-control pairs of adults who had never smoked (identified in the SIREN study) using conditional logistic regression at a two-sided P < 0.05. RESULTS:Multivariable-adjusted odds ratio and 95% confidence interval; 1.25 (1.04, 1.50; P = 0.02) revealed SHSE was positively associated with stroke independent of stroke subtypes. CONCLUSION:Culturally relevant primary prevention strategies targeted at SHSE might be promising in preventing stroke among Africans.

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