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Progranulin promotes proliferation, migration and invasion via the PI3K/Akt signalling pathway in a model of endometriosis

Rongyan Qin,Fengque Zheng,Weili Qin,Jiawei Wang,Nana Ma,Wencai Tian,Jiaxu Li,Ming Liao,Aiping Qin

Reproductive BioMedicine Online（2023）

Cited 1|Views7
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Abstract
•High-purity primary eutopic endometrial stromal cells were successfully isolated•The levels of PGRN expression were significantly elevated in endometriosis tissue samples•PGRN promoted the proliferation, migration and invasion of endometrial stromal cells•These effects are achieved via the PI3K/Akt signalling pathway
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Key words
Endometriosis,Invasion,Migration,Primary eutopic endometrial stromal cells
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