CAPN8 involves with exhausted, inflamed, and desert immune microenvironment to influence the metastasis of thyroid cancer.

Xiang Zhong,Shu Xu,Quhui Wang,Long Peng,Feiran Wang,Tianyi He,Changyue Liu,Sujie Ni,Zhixian He

Frontiers in immunology（2022）

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摘要

The present study firstly explored the role of CAPN8 in the metastasis of THCA from the aspects of TIME. Three immune subtypes were identified with quite different patterns of prognosis, immunotherapy response, and drug sensitivity, providing novel insights for the treatment of THCA and helping understand the cross-talk between CAPN8 and tumor immune microenvironment.

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关键词

CAPN8,immunotherapy,prognosis,thyroid cancer,tumor immune microenvironment

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