MUC22, HLA-A, and HLA-DOB variants and COVID-19 in resilient super-agers from Brazil.
Frontiers in immunology(2022)
摘要
Since the pro-inflammatory basal state in the elderly may enhance the susceptibility to severe Covid-19, we hypothesized that might play an important protective role against severe Covid-19, by reducing overactive immune responses in the senior population.
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关键词
COVID-19,HLA,MUC22,SARS-CoV-2,human leukocyte antigens,immune response,major histocompatibility complex (MCH),resistant genetic variants
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