Negative results of bronchoalveolar lavage fluid metagenomic next-generation sequencing in critically ill patients.

Wentao Ma,Yangchao Zhao,Xiaoxiao Lu,Li Zhang,Xiaoxu Ma,Jing Gao,Junna Hou,Qiuhong Liu,Shilong Zhao,Mengying Yao,Lihua Xing

Frontiers in cellular and infection microbiology（2022）

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摘要

Negative results of BALF mNGS can help to rule out infection, but missed diagnoses may also exist. It should be re-evaluated with other clinical informations. Pathological examination or repeated mNGS may be viable options when the diagnosis cannot be confirmed.

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关键词

bronchoalveolar lavage fluid (BALF),clinical diagnosis,metagenomic next-generation sequencing (mNGS),negative results,pathological examination

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