First-line treatments for patients with advanced ALK gene rearrangements in NSCLC: a systematic review and network meta-analysis.

The Journal of international medical research(2022)

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摘要
Lorlatinib was associated with the best PFS overall, and was suitable for patients with or without brain metastases. Brigatinib was associated with the best PFS in Asian patients.
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关键词
ALK inhibitors,Non-small cell lung cancer,anaplastic lymphoma kinase,brigatinib,first-line therapy,lorlatinib
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