Metabolome profiles for pancreatic cancer risk prediction
Pancreatology(2022)
摘要
We describe here a straightforward strategy towards the high yield preparation of raspberry-like all-organic particles. Poly(acrylic acid)-b-poly(butyl acrylate) core–shell nanoparticles (D ∼ 80 nm) and larger poly(ethylene oxide)-b-poly(butyl acrylate) core–shell (D ∼ 230 nm), synthesized by RAFT emulsion polymerization, were mixed at high solids content (23 wt%) at room temperature without any particular precaution (no dropwise addition, no pH adjustment). Raspberry-like particles constituted of one central PEO-b-PBA particle surrounded by about thirty PAA-b-PBA particles were successfully obtained, with no coagulum formation. The heteroaggregation process is probably driven by the hydrogen-bond interactions between the PAA and the PEO shells of the particles. The raspberry-like particles were characterized using electron microscopy (TEM and cryo-TEM), dynamic light scattering (DLS), chromatography (HDC) and calorimetry (ITC), demonstrating the selectivity of the process.
更多查看译文
关键词
cancer,prediction
AI 理解论文
溯源树
样例
![](https://originalfileserver.aminer.cn/sys/aminer/pubs/mrt_preview.jpeg)
生成溯源树,研究论文发展脉络
Chat Paper
正在生成论文摘要