Polymorphic variants involved in methylation regulation: a strategy to discover risk loci for pancreatic ductal adenocarcinoma.
Chiara Corradi,Giulia Lencioni,Manuel Gentiluomo,Alessio Felici,Anna Latiano,Gediminas Kiudelis, Casper H J van Eijck,Katalin Marta,Rita T Lawlor,Francesca Tavano,Ugo Boggi,Frederike Dijk,Giulia Martina Cavestro,Roel C H Vermeulen,Thilo Hackert, Maria Chiara Petrone,Faik Güntac Uzunoğlu, Livia Archibugi,Jakob R Izbicki,Luca Morelli, Alessandro Zerbi,Stefano Landi,Hannah Stocker,Renata Talar-Wojnarowska,Gregorio Di Franco, Péter Hegyi,Cosimo Sperti, Silvia Carrara, Gabriele Capurso,Maria Gazouli, Hermann Brenner,Stefania Bunduc,Olivier Busch, Francesco Perri,Martin Oliverius, Péter Jeno Hegyi,Mara Goetz,Pasquale Scognamiglio,Andrea Mambrini, Paolo Giorgio Arcidiacono,Edita Kreivenaite,Juozas Kupcinskas,Tamas Hussein,Stefano Ermini,Anna Caterina Milanetto,Pavel Vodicka,Vytautas Kiudelis,Viktor Hlaváč,Pavel Soucek,George E Theodoropoulos,Daniela Basso,John P Neoptolemos,Mateus Nóbrega Aoki, Raffaele Pezzilli,Claudio Pasquali,Roger Chammas,Sabrina Gloria Giulia Testoni,Beatrice Mohelnikova-Duchonova,Maurizio Lucchesi,Cosmeri Rizzato,Federico Canzian,Daniele Campa Pancreatology（2023）
摘要
We identified a novel PDAC risk locus which modulates cancer risk by controlling gene expression through DNA methylation.
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关键词
methylation regulation,polymorphic variants,risk loci
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