The Second Generation Type II JAK2 Inhibitor, AJ1-10502, Demonstrates Enhanced Selectivity, Improved Therapeutic Efficacy and Reduced Mutant Cell Fraction Compared to Type I JAK2 Inhibitors in Models of Myeloproliferative Neoplasms (MPNs)

Shivam Rai,Jan Stetka,MARC Usart,Hui Hao-Shen,Young Park,Remie Houston, Anthony R. Martinez Benitez, Matthew Wereski,Emily Guzzardi, Sonali Persaud, Hailey Ramzan, Alan Futran, Charley Xu,Jeremy Greenwood,Sayan Mondal, Craig Masse,Ross L. Levine,Radek C. Skoda,Andrew Dunbar

Blood(2022)

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jak2 inhibitors,myeloproliferative neoplasms
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