Rapid and direct quantification of the SARS-CoV-2 virus with an ultrasensitive nanobody-based photonic nanosensor

Gisela Ruiz-Vega,Maria Soler,M. Carmen Estevez,Patricia Ramirez-Priego,Martalu D. Pazos, María A. Noriega,Yago Margolles,Clara Francés-Gómez,Ron Geller,Giulia Matusali,Francesca Colavita,Antonino di Caro,José M. Casasnovas,Luis Angel Fernández,Laura M. Lechuga

Sensors & diagnostics（2022）

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摘要

An innovative nanophotonic sensor using bioengineered nanobodies as receptors enables ultrasensitive COVID-19 detection and viral load determination in a 15 min assay without sample pretreatments.

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