Flash drug release from nanoparticles accumulated in the targeted blood vessels facilitates the tumour treatment

Ivan V. Zelepukin,Olga Yu. Griaznova,Konstantin G. Shevchenko,Andrey V. Ivanov,Ekaterina V. Baidyuk,Natalia B. Serejnikova,Artur B. Volovetskiy,Sergey M. Deyev,Andrei V. Zvyagin

Nature Communications（2022）

引用 8|浏览8

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摘要

Achieving the delivery of drugs into the centre of solid tumours is a challenge due to the tumour micro-environment. Here, the authors propose a system for using the rapid release of large quantities of drug inside tumour microcapillaries for the gradient-driven diffusion of drugs into solid tumours.

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