Imaging mass spectrometry reveals complex lipid distributions across Staphylococcus aureus biofilm layers

Emilio S. Rivera,Andy Weiss,Lukasz G. Migas,Jeffrey A. Freiberg,Katerina V. Djambazova,Elizabeth K. Neumann,Raf Van de Plas,Jeffrey M. Spraggins,Eric P. Skaar,Richard M. Caprioli

Journal of Mass Spectrometry and Advances in the Clinical Lab（2022）

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摘要

Three distinct horizontal layers are visible within the cross section of an S. aureus biofilm where some cardiolipin species such as CL(61:0) are more abundant in the top layer (red), and other species such as CL(62:0) are more abundant in the bottom layer (blue).

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关键词

Imaging Mass Spectrometry,Trapped Ion Mobility,Biofilms,Lipids

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