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The influence of GBA and LRRK2 on mood disorders in Parkinson's Disease

A. Thaler,N. Omer,B. Cohen,N. Giladi,M. Kestenbaum,J. Shirvan,J. Cedarbaum,M. Gana-Weisz,O. Goldstein,A. Orr-Urtreger,A. Mirelman

MOVEMENT DISORDERS（2022）

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Abstract
Prodromal -PD are more frequently treated with mood related-medications despite equal rates of reported mood-related disorders, while -PD with mood-related disorders experience high rates of anxiety and depression despite treatment, attesting to the need of more precise assessment and treatment of these genetic subgroups.
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Key words
GBA,LRRK2,Parkinson's disease,anxiety,depression
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