POINT OF CARE TESTING FOR HYPERLIPIDEMIA: LIMITATIONS AND BENEFITS

T. Martinez, B. M. M. Almeida, A. Saldanha, C. Q. Cardoso, M. Scartezini,L. Malucelli, C. C. Klosovski, A. P. P. Margeotto, A. L. Gasparoto,A. Pereira, T. Bellincanta

ATHEROSCLEROSIS(2022)

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Abstract
Background and Aims : Point od Care testing has become a form of technique universally used not only for epidemiological research but as follow up control for patients under treatment. It has limitations aswell as to presenting results only between two values,a lower and an upper value limits.Even so,focusing in its official purposes ,it is a most important way of mapping epidemiologically a country or a prefixed region,in which Brazil can be a good example for profiting from a large scale screening.Methods: In this study 8547 individuals ,ages from 20 to 93 years old ,went spontaneously to the collection points for lipid profiles results from the five regions in Brazil.The particular technique was performed using a colorimetric test strip by the Hilab equipment that connects to the internet of things technology that recognizes resultsby each the unique QR code that is sent via cloud to the central resarch center.Linear ranges(mg-ml):Cholesterol and Triglycerides from 120 to 400 and HDLc 20 to 100.Statistical tests applied:chi square,Student t and ANOVA.ResultsResults: Focusing in limitations ,the numbers of participants below(B) and upper(U) the range limits were, in order of numbers and percentiles:Total Cholesterol-B: 1703 and 19,94;U-35 and 0.41%.Triglycerides-B:1692 and 19,81%;U-862 and 10,09%.HDLc-B 111 and 1,3%;U-135 and 1,58%. Benefits:awareness for Familiar Hypercholesterolemia and Familiar Chylomicronemia Syndrome,the limitations can turn out to be a benefit for prevention of cardiovascular diseases and pancreatitis.Conclusions: Point of care tests for lipid profile can be not only a screening for dyslipidemias but an important signalizer too of genetic hyperlipidemias such as Familial Hypercholesterolemia and Familial Chylomicronemia Syndrome . Background and Aims : Point od Care testing has become a form of technique universally used not only for epidemiological research but as follow up control for patients under treatment. It has limitations aswell as to presenting results only between two values,a lower and an upper value limits.Even so,focusing in its official purposes ,it is a most important way of mapping epidemiologically a country or a prefixed region,in which Brazil can be a good example for profiting from a large scale screening. Methods: In this study 8547 individuals ,ages from 20 to 93 years old ,went spontaneously to the collection points for lipid profiles results from the five regions in Brazil.The particular technique was performed using a colorimetric test strip by the Hilab equipment that connects to the internet of things technology that recognizes resultsby each the unique QR code that is sent via cloud to the central resarch center.Linear ranges(mg-ml):Cholesterol and Triglycerides from 120 to 400 and HDLc 20 to 100.Statistical tests applied:chi square,Student t and ANOVA.Results Results: Focusing in limitations ,the numbers of participants below(B) and upper(U) the range limits were, in order of numbers and percentiles:Total Cholesterol-B: 1703 and 19,94;U-35 and 0.41%.Triglycerides-B:1692 and 19,81%;U-862 and 10,09%.HDLc-B 111 and 1,3%;U-135 and 1,58%. Benefits:awareness for Familiar Hypercholesterolemia and Familiar Chylomicronemia Syndrome,the limitations can turn out to be a benefit for prevention of cardiovascular diseases and pancreatitis. Conclusions: Point of care tests for lipid profile can be not only a screening for dyslipidemias but an important signalizer too of genetic hyperlipidemias such as Familial Hypercholesterolemia and Familial Chylomicronemia Syndrome .
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Key words
hyperlipidemia,care testing
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