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Frataxin deficiency alters gene expression in Friedreich ataxia derived IPSC-neurons and cardiomyocytes.

Mariana B Angulo,Alexander Bertalovitz,Mariana A Argenziano,Jiajia Yang,Aarti Patel,Theresa Zesiewicz,Thomas V McDonald

Molecular genetics & genomic medicine（2023）

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Abstract
These results offer novel insight into specific roles of frataxin deficiency pathogenesis in neurons and cardiomyocytes.
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Key words
Friedreich's ataxia,extracellular matrix,frataxin,glycolysis,lentivirus
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