Overlapping genetic susceptibility of seven autoimmune diseases:SPU tests based on genome-wide association summary statistics

Gene(2023)

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摘要
•Our study was designed for more autoimmune diseases, compared to previous studies.•An advanced multivariate statistical analysis model, SPU tests, was applied.•We have analysed 7 high quality GWAS summary statistics.•28 novel shared risk genes and 14 Biological pathways of seven autoimmune diseases were identified.
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关键词
Autoimmune diseases,Pleiotropic gene,SPU tests,GWAS
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