Extracellular vesicles metabolic changes reveals plasma signature in stage-dependent diabetic kidney disease.
Renal failure(2022)
Abstract
Uracil, LPC(O-18:1/0:0), sphingosine 1-phosphate, and 4-acetamidobutyric acid exhibited potential as suitable biomarkers for early DKD diagnosis. Unexpectedly, combining these four candidate metabolites resulted in enhanced predictive ability for DKD.
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Key words
Extracellular vesicle,diabetes mellitus,diabetic kidney disease,exosomes
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