Rapamycin regulates osteogenic differentiation through Parkin-mediated mitophagy in rheumatoid arthritis (vol 113, 109407, 2022)

Qiyue Chen,Kai Fan,Guangbao Song,Xinqiong Wang,Jinwei Zhang,Huan Chen,Xuan Qin,Yao Lu,Weizhong Qi

INTERNATIONAL IMMUNOPHARMACOLOGY（2023）

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摘要

Mitophagy regulatory signaling pathways are involved in the pathological process of RA. Parkin is a crucial component in RAPA activated mitophagy which mediated clearance of damaged mitochondria and promoted osteogenic differentiation in preosteoblasts.

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关键词

Rheumatoid arthritis,Rapamycin,Mitophagy,Parkin,Osteoporosis

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