Single-cell RNA-seq uncovers cellular heterogeneity and provides a signature for paediatric sleep apnoea.

Rene Cortese,Taylor S Adams,Kylie H Cataldo, Justin Hummel,Naftali Kaminski,Leila Kheirandish-Gozal,David Gozal

The European respiratory journal（2023）

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摘要

OSA deregulates systemic immune function and displays a molecular signature that can be assessed in standard cellular RNA without the need for pre-analytical cell separation, thereby making the assay amenable to application in a molecular diagnostic setting.

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关键词

cellular heterogeneity,sleep,single-cell,rna-seq

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