Single-cell profiling reveals mechanisms of uncontrolled inflammation and glycolysis in decidual stromal cell subtypes in recurrent miscarriage.

Shihua Bao,Zechuan Chen,Dengke Qin,Huihui Xu,Xujing Deng,Ruixiu Zhang,Jiaqiang Ma,Zhouping Lu,Shan Jiang,Xiaoming Zhang

Human reproduction (Oxford, England)（2023）

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摘要

This study was supported by the Strategic Priority Research Program (No. XDB29030302), Frontier Science Key Research Project (QYZDB-SSW-SMC036), Chinese Academy of Sciences; National Key Research and Development Program of China (2021YFE0200600), National Natural Science Foundation of China (No. 31770960), Shanghai Municipal Science and Technology Major Project (No. 2019SHZDZX02, HS2021SHZX001), and Shanghai Committee of Science and Technology (17411967800). All authors report no conflict of interest.

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关键词

decidual stromal cell,glycolysis,immune regulation,inflammation,recurrent miscarriage,single-cell RNA sequencing

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