Evolution of an Adenine Base Editor into a Small, Efficient Cytosine Base Editor with Low Off-Target Activity

Monica E. Neugebauer,Alvin Hsu,Mandana Arbab,Nicholas A. Krasnow,Amber N. McElroy,Smriti Pandey,Jordan L. Doman,Tony P. Huang,Aditya Raguram,Samagya Banskota,Gregory A. Newby,Jakub Tolar,Mark J. Osborn,David R. Liu

Nature Biotechnology（2022）

Cited 96|Views53

Key words

Genetic engineering,Targeted gene repair,Life Sciences,general,Biotechnology,Biomedicine,Agriculture,Biomedical Engineering/Biotechnology,Bioinformatics

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