Correction: Characteristics of oral microbiome of healthcare workers in different clinical scenarios: a cross-sectional analysis

Zhixia Zhang, Wenyi Yu, Guangyao Li, Yukun He, Zhiming Shi, Jing Wu, Xinqian Ma, Yu Zhu, Lili Zhao, Siqin Liu, Yue Wei, Jianbo Xue, Shuming Guo, Zhancheng Gao

BMC Oral Health(2022)

引用 0|浏览6
暂无评分
摘要
The environment of healthcare institutes (HCIs) potentially affects the internal microecology of medical workers, which is reflected not only in the well-studied gut microbiome but also in the more susceptible oral microbiome. We conducted a prospective cross-sectional cohort study in four hospital departments in Central China. Oropharyngeal swabs from 65 healthcare workers were collected and analyzed using 16S rRNA gene amplicon sequencing. The oral microbiome of healthcare workers exhibited prominent deviations in diversity, microbial structure, and predicted function. The coronary care unit (CCU) samples exhibited robust features and stability, with significantly higher abundances of genera such as Haemophilus, Fusobacterium, and Streptococcus, and a lower abundance of Prevotella. Functional prediction analysis showed that vitamin, nucleotide, and amino acid metabolisms were significantly different among the four departments. The CCU group was at a potential risk of developing periodontal disease owing to the increased abundance of F. nucleatum. Additionally, oral microbial diversification of healthcare workers was related to seniority. We described the oral microbiome profile of healthcare workers in different clinical scenarios and demonstrated that community diversity, structure, and potential functions differed markedly among departments. Intense modulation of the oral microbiome of healthcare workers occurs because of their original departments, especially in the CCU.
更多
查看译文
关键词
Healthcare institutes,Coronary care unit,Healthcare worker,16S rRNA,Oral microbiome,Microbial alteration
AI 理解论文
溯源树
样例
生成溯源树,研究论文发展脉络
Chat Paper
正在生成论文摘要