Metformin promotes smear conversion in tuberculosis-diabetes comorbidity and construction of prediction models.
Journal of clinical laboratory analysis(2022)
Abstract
This retrospective study of a large population from southwestern China provides strong clinical evidence for the positive effects of metformin in TB-DM. Metformin is associated with a better therapeutic outcome and promising for the adjuvant therapy of TB-DM. Furthermore, a combination of support vector machine and LR models is recommended to discriminate the patients with poor treatment outcomes.
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Key words
diabetes mellitus,metformin,prediction model,smear conversion,tuberculosis
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