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Omicron BA.5 Neutralization among Vaccine-Boosted Persons with Prior Omicron BA.1/BA.2 Infections.

Rune M Pedersen,Line L Bang,Ditte S Tornby,Lone W Madsen,Dorte K Holm,Thomas V Sydenham,Isik S Johansen,Thøger G Jensen,Ulrik S Justesen,Thomas E Andersen

Emerging infectious diseases（2022）

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Abstract
Worldwide, millions of persons have received multiple COVID-19 vaccinations and subsequently recovered from SARS-CoV-2 Omicron breakthrough infections. In 2 small, matched cohorts (n = 12, n = 24) in Denmark, we found Omicron BA.1/BA.2 breakthrough infection after 3-dose BNT162b2 vaccination provided improved Omicron BA.5 neutralization over 3-dose vaccination alone.
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Key words
BA.1,BA.2,BA.5,COVID-19,Omicron,SARS,SARS-CoV-2,coronavirus,coronavirus disease,respiratory infections,severe acute respiratory syndrome coronavirus 2,vaccines,viruses,zoonoses
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