Measuring saccades in patients with Niemann-Pick type C: A comparison between video-oculography and a novel eye tracking test based on continuous psychophysics.

A Grillini,L H Koens,G Lizaitiene,F Lange,F W Cornelissen, M A J Tijssen

Clinical parkinsonism & related disorders（2022）

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摘要

SONDA reveals a deterioration of vertical saccades in NP-C patients that is consistent with VOG. SONDA's measures based on continuous psychophysics are consistent with traditional saccadic parameters and can potentially provide complementary information. SONDA shows larger effect sizes than VOG, suggesting that it provides robust and clinically relevant outcomes with a more intuitive task and shorter testing time.

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关键词

Eye movement disorders,NP-C, Niemann-Pick type C,Niemann-Pick type C,SONDA,SONDA, Standardized Oculomotor and Neuro-ophthalmic Disorders Assessment,VOG,VOG, Video-oculography,VSGP, Vertical supranuclear gaze palsy,Vertical supranuclear gaze palsy

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