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Meta-analysed numbers needed to treat of novel antidiabetic drugs for cardiovascular outcomes.

Georg Wolff,Yingfeng Lin,Cihan Akbulut,Maximilian Brockmeyer,Claudio Parco,Alexander Hoss,Alexander Sokolowski,Ralf Westenfeld,Malte Kelm,Michael Roden,Sabrina Schlesinger,Oliver Kuss

ESC heart failure（2023）

Cited 2|Views26
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Abstract
We found only modest treatment benefits of GLP-1 receptor agonists and SGLT2 inhibitors for CM and HHF in primary type 2 diabetes mellitus populations. In primary heart failure populations, SGLT2 inhibitor benefits were substantial and comparable in efficacy to established heart failure medication.
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Key words
Absolute treatment effect,GLP-1 receptor agonist,Heart failure,Meta-analysis,Number needed to treat,SGLT2 inhibitor
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