2,4-Bis(2,4-dimethoxyphenyl)-1,3-dithia-2,4-diphosphetane 2,4-disulfide and its derivatives: Syntheses, structural characterizations, anticancer activities, and theoretical studies on some dithiophosphonato Ni(II) complex

Ertuğrul Gazi Sağlam,Elif Bulat,Celal Tuğrul Zeyrek,Senem Akkoç,Yunus Zorlu,Hamza Yılmaz

Journal of Molecular Structure（2023）

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Abstract

•2,4-bis(2,4-dimethoxyphenyl)−1,3-dithia-2,4-diphosphetane 2,4-disulfide and its derivatives were synthesized and characterized for the first time.•Single crystal X-ray diffraction analysis and theoretical studies of the Ni(II) complex was performed.•In vitro cytotoxic activities of the compounds were studied.

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Key words

Perthiophosphonic acid anhydrides,2,4-diorganyl-1,3,2,4-dithiadiphosphetan-2,4-disulfide,Phosphonodithioates,Dithiophosphonates,Organodithiophosphorus compounds,Single crystal X-ray analysis,Density functional theory,Molecular docking,Antiproliferative activity,Anticancer

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