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Comparing BamHI-W and CE-marked assays to detect circulating Epstein-Barr Virus (EBV) DNA of nasopharyngeal cancer patients in a non-endemic area

Francesca Taverna,Salvatore Alfieri,Rebecca Romanò,Giulia Campanini,Sara Marceglia,Federica Giardina,Arabella Mazzocchi,Patrizia Comoli, Annunziata Gloghini,Pasquale Quattrone,Cristiana Bergamini,Giulia Apollonio,Daria Maria Filippini, Ester Orlandi,Laura Deborah Locati,Lisa Licitra,Fausto Baldanti,Paolo Bossi

Oral Oncology（2022）

Cited 1|Views8
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Abstract
•Plasma EBV-DNA is a prognostic biomarker in NPC clinical management.•Multiple- (BamHI-W) vs single-copy gene (CE-marked) assays can detect EBV-DNA.•Commutability between BamHI-W vs CE-marked assays is advocated.•BamHI-W vs three CE-marked assays agreed in plasma EBV-DNA quantification.•Whole blood detected more post-treatment EBV-DNA positive samples than plasma.
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Key words
Epstein-Barr Virus (EBV),nasopharyngeal carcinoma (NPC),Polymerase chain reaction (PCR),Circulating,Biomarker,Liquid biopsy
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