Realization of single and double cole tissue models using higher order approximation

This paper brings a design methodology of biological tissues that exhibits Single Cole and Double Cole model. These tissue models are based on fractional order RC ladder logic design. The Nyquist plots for these Cole models are obtained after finding the impedance parameters by using very familiar indirect measurement scheme like Continued Fraction Expansion (CFE) method. For getting the wide range of frequency 10 terms of CFE is considered for better result. Biological tissue Modeling based on fractional order circuit model have practical applications in biomedicine and bioengineering. The fractional order biological tissue models and its related impedance plots obtained through PSPICE simulation.