Role of reactive oxygen species in high concentration glucose-induced growth inhibition of human peritoneal mesothelial cells.

Both HG and exogenous HO treatments can induce growth inhibition of HPMCs by arresting cell cycle progression, which is partially due to the increased expression of and . Thus, the effects of HG might be associated with endogenous reactive oxygen species (ROS), and it might be beneficial to use antioxidants in peritoneal dialysis (PD).