Evolution of lung adenocarcinoma from preneoplasia to invasive adenocarcinoma.

Jianfei Zhu,Wenchen Wang,Yanlu Xiong,Shuonan Xu, Jiankuan Chen,Miaomiao Wen,Yabo Zhao,Jie Lei,Tao Jiang

Cancer medicine（2023）

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摘要

The accumulation of EGFR driver gene mutation frequencies mediates the progression of LUAD from AIS to MIA. When the tumour progresses to stage IA invasive adenocarcinoma, multivariate analysis based on driver gene status can be used as a pivotal prognostic factor.

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关键词

adenocarcinoma in situ,drive gene,invasive adenocarcinoma,prognosis

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