Clinical outcomes of tucidinostat-based therapy after prior CDK4/6 inhibitor progression in hormone receptor-positive heavily pretreated metastatic breast cancer.
Breast (Edinburgh, Scotland)(2022)
Abstract
This study preliminarily shows that tucidinostat combined with endocrine therapy may be an optional sequential strategy for patients with HR+/HER2-advanced breast cancer that has progressed on CDK4/6 inhibitor, especially for these with lower tumor burden and fewer prior palliative treatment.
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Key words
CDK4/6 inhibitor,Endocrine therapy,Hormone receptor-positive,Metastatic breast cancer,Tucidinostat
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