Effectiveness of the Fiocruz recombinant ChadOx1-nCoV19 against variants of SARS-CoV-2 in the Municipality of Botucatu-SP.

Sue Ann Costa Clemens,Carlos Magno Castelo Branco Fortaleza,Madeleine Crowe,Karen Ingrid Tasca,André Gasparini Spadaro,Jayme Augusto Souza-Neto,Rejane Maria Tommasini Grotto, Regina Sider,Jose Jimeno,Thomas Verstraeten,Ralf Clemens

Frontiers in public health（2022）

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摘要

This observational study found the effectiveness of ChadOx1-nCoV19 to be 74.5% against COVID-19 disease of any severity, comparable to the efficacy observed in clinical trials (81.3% after dose 2), despite the dominance of the Gamma and Delta VoCs. No COVID-19-related hospitalizations or deaths in fully vaccinated individuals were reported.

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COVID-19,ChadOx1,effectiveness,vaccines,variants of concern,“real world” study

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